Involvement of the chemokine RANTES (CCL5) in resistance to experimental infection with Leishmania major.
نویسندگان
چکیده
The expression and putative role of chemokines during infection with Leishmania major in mice were investigated. CCL5 expression correlates with resistance, and blockade of CCL5 rendered mice more susceptible to infection. CCL5 is part of the cascade of events leading to efficient parasite control in L. major infection.
منابع مشابه
Chemokine gene expression in toll-like receptor-competent and -deficient mice infected with Leishmania major.
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ورودعنوان ژورنال:
- Infection and immunity
دوره 72 8 شماره
صفحات -
تاریخ انتشار 2004